Webinar:
CAR T cells live and up-close:
Metabolic engineering for enhanced function
Understanding the balance between T cell killing, persistence, and exhaustion is the essential basis for creating effective CAR T cell therapies for cancer and auto-immune conditions. How can heterogeneous T cell responses be studied, and how can CAR T cells be enhanced for improved persistence and efficacy?
Join us for a webinar presented by Dr Roddy O’Connor, Research Assistant Professor at University of Pennsylvania’s renowned Center for Cellular Immunotherapies and expert in CAR T activity and metabolism, as he examines how CAR T cell killing can be optimized through metabolic engineering.
Using Nanolive’s unique imaging and analysis platform, Dr O’Connor will investigate how CAR T cells fuel their cytotoxic activity and interact with target cancer cells, using AI-powered analysis to quantify label-free live cell imaging data. Additionally, he will investigate the behavior of CAR T cells at the single cell level, exploring high-resolution live captures of serial killing, co-operative killing, and exhaustion.
Watch to discover:
How many tumor cells can a single CAR T cell can kill in 7 hours?
How fast do CAR T cells move?
Can CAR T killing be boosted by a change of fuel?
Does T cell-target interaction guarantee successful killing?
This online event is ideal for scientists in immuno-oncology who are looking to:
- Gain deeper insights into immune cell behavior and cell:cell interactions
- Accelerate screening and candidate selection with high-content data
- Eliminate phototoxicity in sensitive cells and preserve their natural behavior
- Get dynamic, real-time data, moving beyond the limits of endpoint assays
- Streamline workflows, reduce hands-on time, and increase reproducibility with scalable, automated analysis
- Support more informed, unbiased decision-making with label-free data
Host
Speaker

Hope Amos
Scientific Communications Specialist
Nanolive

Dr Roddy O’Connor
Research Assistant Professor
Center for Cellular Immunotherapies,
University of Pennsylvania