Discover the advanced capabilities of Nanolive’s LIVE Cytotoxicity Assay in an application note. This document presents a detailed exploration of how our innovative, label-free technology enables researchers to monitor phenotypic changes and detect cell stress accurately before it leads to cell death. Explore how our unique approach enhances the predictive value of cytotoxic assays and supports high-content data generation without the use of harmful dyes or markers.
A cutting-edge approach to cell health and stress with Nanolive’s LIVE Cytotoxicity Assay
Discover how to:
- Detect cell stress and its dynamics from an early stage
- Capture the detailed morphological changes that precede cell death
- Track apoptosis and necrosis simultaneously and label-free
- Monitor cells long-term, without compromising their health with fluorescent markers or chemical dyes
Case studies from the Phenotypic Cell Health and Stress Application Note
Explore the impact of Nanolive’s technology through our detailed case studies, highlighting its effectiveness in practical applications.
Case Study 1: Monitoring cell stress with the health cell index
See how Nanolive can be used for early detection of the transition from healthy, to stressed and dying cells, before detection of cell death is possible using traditional endpoint assays.
Case study 2: Detecting anastasis (reversible apoptosis)
This case study shows how the LIVE Cytotoxicity assay can be used to detect cells which enter apoptosis and return to a healthy phenotype (anastasis). This approach can be used to monitor cancer cells during drug screening, as any populations that become stressed, but do not die are more at risk of developing drug resistance.
Nanolive’s label-free high-content imaging alleviates the limitations of endpoint assays and chemical markers, producing unbiased temporal data.
Find out more in our Application Note.
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