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Exploring the influence of the glycone space on the therapeutic potential of sp2-iminoglycolipids

Jul 30, 2025

Authors: M. Carmen Padilla-Pérez, Rocío Rodríguez-Marín, Aday González-Bakker, Adam N. Khan, Mariana Bastardo-Torío, José M. Padrón, Francisco Martín-Loro, Ana I. Arroba, Raquel García-Hernández, José M. Pérez-Victoria, José M. García Fernández, Elena M....

Flemiphilippinin A induces paraptosis in lung cancer cells via c-Myc-driven endoplasmic reticulum stress and CHOP-mediated mitochondrial dysfunction

Jul 23, 2025

Authors: Zhipeng Xu, Xiaodong Huang, Qian Su, Qinqin Wang, Lina Liu, Yufang Shen, Lianting Liao, Xianmin Zou, Shilin Yang, Yunli Tang, Hongwei Gao, Renyikun Yuan https://doi.org/10.1016/j.phymed.2025.157098, 2025 Published in: Phytomedicine Tags: Flemiphilippinin A;...

Caulerpin Delivery via Pluronic-Free Cubosomes: Unlocking the Therapeutic Potential of a Pigment from an Invasive Marine Algae

Jul 2, 2025

Authors: Karolina Krautforst, Julita Kulbacka, Marco Fornasier, Rita Mocci, Andrea Porcheddu, Antonio Pusceddu, Davide Moccia, Sergio Murgia, Urszula Bazylińska https://doi.org/10.1021/acs.molpharmaceut.5c00340, 2025 Published in: Molecular Pharmaceutics Tags: Algae;...

Design, Anticancer Activity, and Mechanistic Evaluation of a Novel Class of Selective Human Carbonic Anhydrase IX Inhibitors Featuring a Trifluorodihydroxypropanone Pharmacophore

Jun 30, 2025

Authors: Nicolino Pala, Federico Ladu, Wojciech Szlasa, Roberta Cadoni, Carrie Lomelino, Brian P. Mahon, Mitchell Gulkis, Robert McKenna, Alessandro Dessì, Roberto Dallocchio, Antonio Demelas, Mauro Carcelli, Dominga Rogolino, Claudia Crosio, Ciro Iaccarino, Julita...

Antiproliferative Withanolides from Jaborosa Riojana

Apr 4, 2025

Authors: Virginia Lobatto Carina N. Casero, Aday González-Bakker, José M. Padrón, and Viviana E. Nicotra https://dx.doi.org/10.2139/ssrn.5197818, 2025 Published in: SSRN Tags: Jaborosa; withanolides; antiproliferative activity; continuous live-cell...

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Exploring the influence of the glycone space on the therapeutic potential of sp2-iminoglycolipids

Flemiphilippinin A induces paraptosis in lung cancer cells via c-Myc-driven endoplasmic reticulum stress and CHOP-mediated mitochondrial dysfunction

Caulerpin Delivery via Pluronic-Free Cubosomes: Unlocking the Therapeutic Potential of a Pigment from an Invasive Marine Algae

Design, Anticancer Activity, and Mechanistic Evaluation of a Novel Class of Selective Human Carbonic Anhydrase IX Inhibitors Featuring a Trifluorodihydroxypropanone Pharmacophore

Antiproliferative Withanolides from Jaborosa Riojana

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