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Flemiphilippinin A induces paraptosis in lung cancer cells via c-Myc-driven endoplasmic reticulum stress and CHOP-mediated mitochondrial dysfunction

Jul 23, 2025

Authors: Zhipeng Xu, Xiaodong Huang, Qian Su, Qinqin Wang, Lina Liu, Yufang Shen, Lianting Liao, Xianmin Zou, Shilin Yang, Yunli Tang, Hongwei Gao, Renyikun Yuan https://doi.org/10.1016/j.phymed.2025.157098, 2025 Published in: Phytomedicine Tags: Flemiphilippinin A;...

Hyaluronic and Succinic Acid: New Biostimulating Combination to Counteract Dermal and Subcutaneous Aging

Jul 22, 2025

Authors: Alfredo Martinez-Gutierrez, Helena Cami, Teresa Noya, Susana Gómez-Escalante, Aina Miró Llosas, Mari Carmen González https://doi.org/10.3390/ijms26157548, 2025 Published in: International Journal of Molecular Sciences Tags: Skin aging; fibroblast senescence;...

Synthetic oleanolic acid derivative, RTA‑408, overcome in TMZ‑resistant glioblastoma cells by inducing apoptosis and G1 cell cycle arrest

Jul 21, 2025

Authors: Kuan‑Ting Lee, Ann‑Shung Lieu, Chih‑Lung Lin, Yi‑Chiang Hsu, Tai‑Hsin Tsai https://doi.org/10.1007/s12032-025-02875-2, 2025 Published in: Medical Oncology Tags: TMZ; omaveloxolone; glioblastoma; resistance

Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype

Jul 19, 2025

Authors: Sébastien Ibanez, Maria Virginia Giolito, Sultan Al-Siyabi, Kristian Serafimov, Florine Laloux, Emeline Dierge, Léo Aubert, Céline Guilbaud, Selena Kaye, Paula Varon, Dorothée Marchand, Hanne Vlieghe, Emmanuel Hermans, Caroline Bouzin, Davide Brusa,...

Mechanistic insights into the anti-aging effects of Crocus sativus in a D-Gal-induced in vitro neural senescence model

Jul 17, 2025

Authors: Vanessa Castelli, Patrizia Cesare, Erjola Bej, Michele d’Angelo, Anna Rita Volpe https://doi.org/10.1371/journal.pone.0320572, 2025 Published in: PLOS ONE  
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