Abrine, an IDO1 inhibitor, suppresses the immune escape and enhances the immunotherapy of anti-PD-1 antibody in hepatocellular carcinoma

Authors: Xiaowei Liang, Hongwei Gao, Jian Xiao, Shan Han, Jia He, Renyikun Yuan, Shilin Yang and Chun Yao

https://doi.org/10.3389/fimmu.2023.1185985, 2023

Published in: Frontiers in Immunology

Tags: Immunooncology, phagocytosis, fluorescence, IDO1, Abrine, CD47, PD-L1, m6A RNA modification, immune escape, hepatocellular carcinoma, macrophages