Stapled Wasp Venom-Derived Oncolytic Peptides with Side Chains Induce Rapid Membrane Lysis and Prolonged Immune Responses in Melanoma

Authors: Ye Wu; Dong Lu; Yixin Jiang; Jinmei Jin; Sanhong Liu; Lili Chen; Hong Zhang; Yudong Zhou; Hongzhuan Chen; Dale G. Nagle; Xin Luan; Weidong Zhang

https://doi.org/10.1021/acs.jmedchem.0c02237, 2021

Published in: Journal of Medicinal Chemistry

Tags: Immunogenic cell death; cytotoxic; peptide stapling; membrane disruption; breast cancer