Scientific Publications
Peer-reviewed research using Nanolive imagingDiscover a list of peer-reviewed scientific publications using Nanolive imaging in the fields of drug discovery, cell metabolism, etc.
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Loss of the TRPM4 channel in humans causes immune dysregulation with defective monocyte migration
Authors: Fang Yu, Satanay Hubrack, Christophe M. Raynaud, Asha Elmi, Rafah Mackeh, Nourhen Agrebi, Gaurav Thareja, Abdelaziz Belkadi,
PhD, Hesham Al Saloos, Ayeda Abdulsalam Ahmed, Saleema C. Purayil, Yasmin A. Mohamoud, Karsten Suhre, Charbel Abi Khalil, Frank Schmidt, Bernice Lo, Amel Hassan, Khaled Machacahttps://doi.org/10.1016/j.jaci.2024.02.026 , 2024
Published in: Journal of allergy and clinical immunology
Tags: TRPM4; immune dysregulation; monocyte; migration; loss of function; infections
Differential effects of coverslip-induced hypoxia and cobalt chloride mimetic hypoxia on cellular stress, metabolism, and nuclear structure.
Authors: Florencia Lamela, Ronell Bologna-Molina, Felipe Parietti, Vanesa Pereira-Prado, Magdalena Millán, Alejandro Silva, Juan Llaguno, Julia Alonso, Ariel Fernández, José Sotelo-Silveira, Manoela Domingues, Miguel Arocena, Jimena Hochmann
https://doi.org/10.1016/j.tice.2024.102408, 2024
Published in: Tissue & Cell
Tags: oxidative stress; hypoxia; metabolism; nuclear structure
Human dendritic cell interactions with the zoonotic parasite Cryptosporidium parvum result in activation and maturation
Authors: Ralf Ross, Seyed Sajjad Hasheminasab, Ivan Conejeros,Ulrich Gärtner,Faustin Kamena, Andreas Krueger, Anja Taubert and Carlos Hermosilla
https://doi.org/10.3389/fimmu.2024.1388366, 2024
Published in: Frontiers in Immunology
Tags: Cryptosporidium parvum, dendritic cells, diarrhea, initiation of adaptive immunity, phagocytosis, small intestine
Biological impact and therapeutic potential of a novel camptothecin derivative (FLQY2) in pancreatic cancer through inactivation of the PDK1/AKT/mTOR pathway
Authors: Wenchao Wang, Haonan Xiong, Lei Li, Xialin Hu, Wenya Zhuang, Jiangtao Li, Xuanrong Sun, Yanlei Yu, Yuanquan Yu, Yinghao Guo, Yihang Wang, Ruojiong Wang, Hong Wang, QingYong Li
https://doi.org/10.1016/j.bioorg.2024.107436, 2024
Published in: Bioorganic Chemistry
Tags: Camptothecin; FLQY2; Organoids; Topoisomerase I; Signaling pathway; Pancreatic cancer
Optogenetically controlled inflammasome activation demonstrates two phases of cell swelling during pyroptosis
Authors: Julien Nadjar, Sylvain Monnier, Estelle Bastien, Anne- Laure Huber, Christiane Oddou, Léa Bardoulet, Hubert B. Leloup, Gabriel Ichim, Christophe Vanbelle, Bénédicte F. Py, Olivier Destaing, Virginie Petrilli
https://doi.org/10.1126/scisignal.abn8003 , 2024
Published in: Science Signalling
Tags: Pyroptosis, cell death
The Glucose Transporter 5 Enhances CAR-T Cell Metabolic Function and Anti-tumour Durability
Authors: Bakir Valentić, Andre Kelly, Alexander A. Shestov, Zhiyang Gan, Feng Shen, Adam Chatoff, Alison Jaccard, Claudia V. Crispim, John Scholler, Simon Heeke, Nathaniel W. Snyder, Saba Ghassemi, Nicholas Jones, Saar Gill, Roddy S. O’Connor
https://doi.org/10.21203/rs.3.rs-4342820/v1, 2024
Published in: Research Square
Tags: T cell velocity, AML, GLUT, CAR-T, immunotherapy, serial killing, tunor microenvironment, LTCA, CX 96focus
Correlating Protein Aggregate Structure with Cellular Function in Differentiated Muscle Cells: Discriminating Pathogenic from Non-Pathogenic Forms
Authors: Sander D. Mallon, Erik Bos, Vahid Sheikhhassani, Milad Shademan, Dino Rocca, Lenard M. Voortman, Alireza Mashaghi, Thomas H. Sharp, Vered Raz
https://doi.org/10.1101/2024.04.25.591067, 2024
Published in: bioRxiv
Tags: protein aggregates, aggregates structure, imaging facilities, PABPN1, OPMD
Optogenetically controlled inflammasome activation demonstrates two phases of cell swelling during pyroptosis
Authors: Julien Nadjar, Sylvain Monnier, Estelle Bastien, Anne- Laure Huber, Christiane Oddou, Léa Bardoulet, Hubert B. Leloup, Gabriel Ichim, Christophe Vanbelle, Bénédicte F. Py, Olivier Destaing, Virginie Petrilli
Published in: Science Signalling
Tags: Pyroptosis, cell death, inflammation, cell swelling, membrane rupture
Biological autoluminescence enables effective monitoring of yeast cell electroporation
Authors: Martin Bereta, Michal Teplan, Tomáš Zakar, Hoang Vuviet, Michal Cifra, Djamel Eddine Chafai
https://doi.org/10.1002/biot.202300475, 2024Published in: Biotechnology Journal
Tags: autoluminescence, electroporation, pulsed electric fields, yeast in biotechnology
Upregulation of EMR1 (ADGRE1) by Tumor-Associated Macrophages Promotes Colon Cancer Progression by Activating the JAK2/STAT1,3 Signaling Pathway in Tumor Cells
Authors: Rokeya Akter, Rackhyun Park, Soo Kyung Lee, Eun ju Han, Kyu-Sang Park, Junsoo Park, and Mee-Yon Cho
Published in: International Journal of Molecular Sciences
Tags: colon cancer; EMR1/ADGRE1; macrophages; JAK2/STAT1,3 signaling; lymph node metastasis