Scientific Publications
Peer-reviewed research using Nanolive imagingDiscover a list of peer-reviewed scientific publications using Nanolive imaging in the fields of drug discovery, cell metabolism, etc.
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Vaccination Against Amyloidogenic Aggregates in Pancreatic Islets Prevents Development of Type 2 Diabetes Mellitus
Authors: Elisa S. Roesti, Christina N. Boyle, Daniel T. Zeman, Marcos Sande-Melon, Federico Storni, Gustavo Cabral-Miranda, Alexander Knuth, Thomas A. Lutz, Monique Vogel and Martin F. Bachmann
DOI: https://doi.org/10.3390/vaccines8010116, 2020
Published in: Vaccines
Tags: Immunology, type 2 diabetes mellitus, T2DM, diabetes, insulin, amyloid deposits, islet amyloid polypeptide (IAPP), pancreas, pancreatic islets, virus-like particles, VLPs, hyperglycemia, cytokine, IL-1b
Stimuli-sensitive fatty acid-based microparticles for the treatment of lung cancer
Authors: Katarzyna Reczyńska, Patrycja Marchwica, Dipesh Khanal, Tomasz Borowik, Marek Langner, Elżbieta Pamuła, Wojciech Chrzanowski
DOI: https://doi.org/10.1016/j.msec.2020.110801, 2020
Published in: Materials and Science Engineering: C
Tags: Immunooncology & oncology, single cell characterization, drug discovery, lung cancer, cancer therapy, superparamagnetic iron oxide nanoparticles, SPION, solid lipid microparticles, lipid, stimuli-sensitive drug carriers, anticancer drug, paclitaxel, lauric acid, LAU, myrisctic acid, palmitic acid, MYR, PAL, cell viability
Neutrophils are mediators of metastatic prostate cancer progression in bone
Authors: Costanzo-Garvey, D.L., Keeley, T., Case, A.J. et al.
DOI: https://doi.org/10.1007/s00262-020-02527-6, 2020
Published in: Cancer Immunology, Immunotherapy
Tags: Immunooncology & oncology, single cell characterization, neutrophils, bone, metastasis, prostate, cancer, STAT5, prostrate cancer, BM-Pca, immunotherapy, Pca, neutrophils, infiltration, apoptosis, cancer growth, cytotoxicity
Proinflammatory Effect of Carbon-Based Nanomaterials: In Vitro Study on Stimulation of Inflammasome NLRP3 via Destabilisation of Lysosomes
Authors: Svadlakova, T.; Hubatka, F.; Turanek Knotigova, P.; Kulich, P.; Masek, J.; Kotoucek, J.; Macak, J.; Motola, M.; Kalbac, M.; Kolackova, M.; Vankova, R.; Vicherkova, P.; Malkova, A.; Simeckova, P.; Volkov, Y.; Prina-Mello, A.; Kratochvilova, I.; Fiala, Z.; Raska, M.; Krejsek, J.; Turanek, J
DOI: https://doi.org/10.3390/nano10030418, 2020
Published in: nanomaterials
Tags: Immunology, graphene platelets, carbon nanotubes, inflammasome NLRP3, cathepsin B, macrophages, THP-1, bioresistance, proinflammatory, inflammation, canonical pathway, alternative pathway, MWCNT, PAMPs
Besnoitia besnoiti bradyzoite stages induce suicidal- and rapid vital-NETosis
Authors: Ershun Zhou, Liliana M. R. Silva, Iván Conejeros, Zahady D. Velásquez, Manuela Hirz, Ulrich Gärtner, Philippe Jacquiet, Anja Taubert and Carlos Hermosilla
DOI: https://doi.org/10.1017/S0031182019001707, 2020
Published in: Parasitology
Tags: Host-pathogen interactions, microbiology and biofilms, besnoitia besnoiti, apicomplexan parasite, infection, lipid droplets, lipids, apicomplexa, cholesterol synthesis, GC-MS, lovastatin, zaragozic, tachyzoite, cholesterol esterification, parasite, lectin, LDL, autophagy, NETosis, vital NETosis
Molecular heterogeneity in breast carcinoma cells with increased invasive capacities
Authors: Giulia Negro, Bertram Aschenbrenner, Simona Kranjc Brezar, Maja Cemazar, Andrej Coer, Gorana Gasljevic, Dragana Savic, Maxim Sorokin, Anton Buzdin, Maurizio Callari, Irma Kvitsaridze, Anahid Jewett, Mariela Vasileva-Slaveva, Ute Ganswindt, Prof. Ira Skvortsova, Sergej Skvortsov
DOI: https://doi.org/10.2478/raon-2020-0007, 2020
Published in: The Journal of Association of Radiology and Oncology
Tags: Stem cells, Immunooncology & oncology, single cell characterization, breast cancer, metastasis, carcinoma, invasiveness, fibroblast-like, migration, stem cell, tumor growth, hormone receptor-positive, Her2-positive, triple-negative, hormone-positive, cancer stem cells, molecular profiling
Enhancement of the biological autoluminescence by mito-liposomal gold nanoparticle nanocarriers
Authors: Hadi Sardarabadi, Djamel Eddine Chafai, Fatemeh Gheybi, Pezhman Sasanpour, Hashem Rafii-Tabar, Michal Cifra
DOI: https://doi.org/10.1016/j.jphotobiol.2020.111812, 2020
Published in: Journal of Photochemistry and Photobiology B: Biology
Tags: Mitochondria and cell metabolism, drug discovery, immunooncology & oncology, nanocarrier, mitochondria, biological autoluminescence, BAL, ROS, reactive oxygen species, liposome, gold nanoparticle
Optimized excystation protocol for ruminant Eimeria bovis- and Eimeria arloingi-sporulated oocysts and first 3D holotomographic microscopy analysis of differing sporozoite egress
Authors: Sara López-Osorio, Liliana M.R.Silva, Jenny J.Chaparro-Gutierréz, Zahady D.Velazquez, Anja Taubert, Carlos Hermosilla
DOI: https://doi.org/10.1016/j.parint.2020.102068, 2020
Published in: Parasitology International
Tags: Microbiology and biofilms, host-pathogen interactions, eimeria bobis, Eimeria arloingi, excystation, sporulated, sporozoites, cell-parasite, oocysts, method
PGRMC1 phosphorylation affects cell shape, motility, glycolysis, mitochondrial form and function, and tumor growth
Authors: Bashar M. Thejer, Partho P. Adhikary, Amandeep Kaur et al.
DOI: https://doi.org/10.21203/rs.2.22342/v1, 2020
Published in: BMC Molecular and Cell Biology
Tags: Immunooncology & oncology, mitochondria and cell metabolism, single cell characterization, mitochondria, migration, invasion, metabolism, cytochrome P450, mesenchymal amoeboid transition, proteomics, tumor biology, progesterone receptor membrane component 1, PGRMC1, cancer, energy metabolism, mitochondrial function
Impaired Glycolysis Promotes Alcohol Exposure-Induced Apoptosis in HEI-OC1 Cells via Inhibition of EGFR Signaling
Authors: Hyunsook Kang, Seong Jun Choi, Kye Hoon Park, Chi-Kyou Lee, and Jong-Seok Moon
DOI: https://doi.org/DOI: 10.3390/ijms21020476, 2020
Published in: International Journal of Molecular Sciences
Tags: Neuroscience, single cell characterization, mitochondria and cell metabolism, glycolysis, EGFR signaling, apoptosis, alcohol, HEI-OC1 cells, glucose metabolism, glucose, auditory sytem, apoptosis, hexokinase 1, HK1, AKT phosphorylation