Scientific Publications
Peer-reviewed research using Nanolive imagingDiscover a list of peer-reviewed scientific publications using Nanolive imaging in the fields of drug discovery, cell metabolism, etc.
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A Gain-Of-Function RAC2 Mutation Is Associated With Bone-Marrow Hypoplasia And An Autosomal Dominant Form Of Severe Combined Immunodeficiency
Authors: Chantal Lagresle-Peyrou, Aurélien Olichon, Hanem Sadek, Philippe Roche, Claudine Tardy, Cindy Da Silva, Alexandrine Garrigue, Alain Fischer, Despina Moshous, Yves Collette, Capucine Picard, Jean Laurent Casanova, Isabelle André, Marina Cavazzana
DOI: https://doi.org/10.3324/haematol.2019.230250, 2020
Published in: Haematologica
Tags: Immunology, severe combined immunodeficiencies, SCIDs, T cells, B cells, leukopenia, RAC2 gene, p.G12R, hematopoietic stem cell transplantation, stem cell, gain of function
A potential hydrodynamic mechanism for cytoplasmic transfer between mammalian cells: Cell-projection pumping
Authors: Hans Zoellner, Navid Paknejad, James Cornwell, Belal Chami, Yevgeniy Romin, Vitaly Boyko, Sho Fujisawa, Elizabeth Kelly, Garry W. Lynch, Glynn Rogers, Katia Manova, Malcolm A.S. Moore
DOI: https://doi.org/10.1101/531798, 2020
Published in: BioRxiv
Tags: Single cell characterization, human fibroblasts, malignant cells, tunneling nanotubes, TNT, shed membrane vesicles, cell-projection pumping, CPP
Image-based analysis of living mammalian cells using label-free 3D refractive index maps reveals new organelle dynamics and dry mass flux
Authors: Patrick A. Sandoz, Christopher Tremblay, F. Gisou van der Goot, Mathieu Frechin
DOI: https://doi.org/10.1371/journal.pbio.3000553, 2019
Published in: PLOS Biology
Tags: Single cell characterization, stem cells, lipid droplets, mitochondria, endocytosis, endocytic structures, cell division, spinning, nuclear rotation
E-Cigarette Use Increases Susceptibility to Bacterial Infection by Impairment of Human Neutrophil Chemotaxis, Phagocytosis and NET Formation
Authors: Ross Corriden, Alexander Moshensky, Christine M Bojanowski, Angela Meier, Jason Chien, Ryan K Nelson, Laura E. Crotty Alexander
DOI: https://doi.org/10.1152/ajpcell.00045.2019, 2019
Published in: American Journal of Physiology
Tags: Immunology, single cell characterization, chemotaxis, E-cigarette, human neutrophils, neutrophil extracellular trap, Pseudomonas; reactive oxygen species, sepsis
S-Nitrosothiol Plasma-Modified Surfaces for the Prevention of Bacterial Biofilm Formation
Authors: Zahra Sadrearhami, Rashin Namivandi-Zangeneh, Emily Price, Marta Krasowska, Sameer A Al-Bataineh, Jason Whittle, Edgar H. H. Wong, Anton Blencowe, Cyrille Boyer
DOI: https://doi.org/10.1021/acsbiomaterials.9b01063, 2019
Published in: ACS Biomater. Sci. Eng
Tags: Microbiology and biofilms, host-pathogen interactions, plasma polymerization, antibacterial coating, biofilm, S-nitrosothiol, surface modification, bacterial infection, infection, nosocomial, gram-negative, Pseudomonas aeruginosa
Toxoplasma gondii-induced host cellular cell cycle dysregulation is linked to chromosome missegregation and cytokinesis failure in primary endothelial host cells
Authors: Velásquez ZD, Conejeros , Larrazabal C , Kerner K, Hermosilla C, Taubert A.
DOI: https://doi.org/10.1038/s41598-019-48961-0, 2019
Published in: Scientific Reports
Tags: Host-pathogen interaction, single cell characterization, Microbiology and biofilms, toxoplasma gondii, zoonotic, intracellular, parasite, lysis, cell cylce, cell division, entothelial cells, multi-nucleation, cyclin B1, chromosome, mitotic spindle, cytokinesis, Aurora B, chromosome segregation, cytokinesis
Beyond the suprachiasmatic nucleus: circadian rhythmicity shapes astrocyte morphology and neuronal function in hippocampal area CA1
Authors: John P. McCauley, Maurice A. Petroccione, Lianna Y. D’Brant, Gabrielle C. Todd, Nurat Affinnih, Justin J. Wisnoski, Shergil Zahid, Swasti Shree, Alioscka A. Sousa, Rosanna Migliore, Alexey Brazhe, Richard D. Leapman, Alexander Khmaladze, Alexey Semyanov, Michele Migliore and Annalisa Scimemi
DOI: https://doi.org/10.1101/666073, 2019
Published in: bioRxiv
Tags: Neuroscience, single cell characterization, suprachiasmatic nucleus, SCN, hypothalamus, rhythmic activity, memory-dependent, hippocampus, CA1, circadian rhythmicity, synaptic transmission, pyramidal neurons, NMDA receptors, astrocytes
Autophagosome accumulation-mediated ATP energy deprivation induced by penfluridol triggers nonapoptotic cell death of lung cancer via activating unfolded protein response
Authors: Wen-Yueh Hung, Jer-Hwa Chang, Yu Cheng, Guo-Zhou Cheng, Hsiang-Ching Huang, Michael Hsiao, Chi-Li Chung, Wei-Jiunn Lee and Ming-Hsien Chien
DOI: https://doi.org/10.1038/s41419-019-1785-9, 2019
Published in: Cell Death & Disease
Tags: Drug discovery, immunooncology & oncology, mitochondria and cell metabolism, anticancer, chemotherapy, apoptosis, autophagy, drug discovery, penfluridol, lung cancer, antitumor, non-small-cell lung cancer, NSCLC, orthotopic xenograft model, viability, motility, p38
Quantification of changes in cellular morphology during cell necrosis obtained from 3D refractive index distributions
Authors: D A Gorbenko, A V Belashov, T N Belyaeva, E S Kornilova, I V Semenova and O S Vasyutinskii
DOI: https://doi.org/10.1088/1742-6596/1236/1/012015, 2019
Published in: Journal of Physics
Tags: Single cell characterization, photodynamic treatment, cellular morphology, apoptosis, necrosis, cell membrane
Pleiotropic Effects of Epithelial Mesenchymal Crosstalk on Head and Neck Cancer: EMT and beyond
Authors: T. B. Steinbichler, D. Savic, D. Dejaco, A. Romani, B. Kofler, I. I. Skvortsova, H. Riechelmann, J. Dudas
DOI: https://doi.org/10.1007/s12307-019-00228-y, 2019
Published in: Cancer Microenvironment
Tags: Drug discovery, immunooncology & oncology, mitochondria and cell metabolism, epithelial mesenchymal crosstalk, EMC, tumor, tumor stroma, associated fibroblasts, cancer, head and neck cancer, chemotherapy, IL-6, JAK/STAT3/Snail signalling, radiochemotherapy, therapy resistance, conditioned medium