Scientific Publications
Peer-reviewed research using Nanolive imagingDiscover a list of peer-reviewed scientific publications using Nanolive imaging in the fields of drug discovery, cell metabolism, etc.
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Refractive index as an indicator for dynamic protein condensation in cell nuclei
Authors: Orlando Marin, Peter Kirchweger, Arina Dalaloyan, Yoav Barak, Michael Elbaum
https://doi.org/10.1101/2025.04.18.647244, 2025
Published in: bioRxiv
A phenotypic screen identifies xanthohumol and other flavonoids as killers of bladder cancer
Authors: Michael J. Bolt, Jessica Oceguera, Alejandra Rivera Tostado, Christopher D. Candler, Elina Mosa, Kazem Safari, Maureen G. Mancini, Michael A. Mancini
https://doi.org/10.1016/j.prenap.2025.100236, 2025
Published in: Pharmacological Research – Natural Products
Tags: Cell paint; phenotypic screening; bladder cancer; xanthohumol
Metabolic rewiring caused by mitochondrial dysfunction promotes mTORC1-dependent skeletal aging
Authors: Kristina Bubb, Julia Etich, Kristina Probst, Tanvi Parashar, Maximilian Schuetter, Frederik Dethloff, Susanna Reincke, Janica L. Nolte, Marcus Krüger, Ursula Schlötzer-Schrehard, Julian Nüchel, Constantinos Demetriades, Patrick Giavalisco, Jan Riemer, Bent Brachvogel
https://www.science.org/doi/full/10.1126/sciadv.ads1842, 2025
Published in: Science Advances
Polarization Gratings Aided Common-Path Hilbert Holotomography for Label-Free Lipid Droplets Content Assay
Authors: Piotr Zdańkowski, Julianna Winnik, Mikołaj Rogalski, Marcin J. Marzejon, Emilia Wdowiak, Wioleta Dudka, Michał Józwik, Maciej Trusiak
https://doi.org/10.1002/lpor.202401474, 2025
Published in: LASER & PHOTONICS REVIEWS
Tags: Holographic microscopy; holotomography; optical diffraction tomography; phase microscopy; quantitative phase imaging
Glioblastoma targeting by water-soluble hypericin derivate HHL-PVP and photodynamic tumour killing
Authors: Djenana Vejzovic, Andreas Kubin, Karoline Fechter, Christina Karner, Jaana Hartmann, Thomas Ackerbauer, Branislav Radović, Gerald Ritter, Muammer Üçal, Stefan Ropele, Kariem Mahdy Ali, Mario Mischkulnig, Marlene Leoni, Bernadette Liegl-Atzwanger, Lionel Wightman, Beate Rinner
https://doi.org/10.1016/j.biopha.2025.118041, 2025
Published in: Biomedicine & Pharmacotherapy
Tags: Water-soluble hypericin; (HHL-PVP); proof-of-principle; photodynamic therapy; orthotopic models; patient-derived glioblastoma cells; glioblastoma multiforme
Staphylococcus aureus β-hemolysin impairs oxygen transport without causing hemolysis
Authors: Qi Li, Nan Chena, Chenghua Liu, Zhen Zhao, Minjun Huang, Jingjing Li, and Guang Yang
https://doi.org/10.1080/21505594.2025.2490208, 2025
Published in: Virulence
Tags: S. aureus, β-hemolysin; sphingomyelinase; RBC; oxygen release
Electromechanical Regulation Underlying Protein Nanoparticle-Induced Osmotic Pressure in Neurotoxic Edema
Authors: Zihui Zheng, Aobo Nie, Xiaojie Wu, Shi Chen, Lijun Zhang, Dongqing Yang, Yuqing Shi,Xiyu Xiong, Jun Guo
https://doi.org/10.2147/IJN.S503181, 2025
Published in: International Journal of Nanomedicine
Tags: Protein nanoparticle; electromechanical cooperation; osmotic tension; membrane potential; neuronal swelling
Antiproliferative Withanolides from Jaborosa Riojana
Authors: Virginia Lobatto Carina N. Casero, Aday González-Bakker, José M. Padrón, and Viviana E. Nicotra
https://dx.doi.org/10.2139/ssrn.5197818, 2025
Published in: SSRN
Tags: Jaborosa; withanolides; antiproliferative activity; continuous live-cell imaging
Nuclear-Targeted Material Enabled Intranuclear MicroRNA Imaging for Tracking Gene Editing Process
Authors: Jiayan Wu, Meng Meng, Zhaopei Guo, Kai Hao, Yonghao Liang, Hanyu Meng, Guanhe Fang, Zongwei Shi, Xiaoya Guo, Huixin Li, Yuanji Feng, Lin Lin, Jie Chen, Yingchao Zhang, Huayu Tian, Xuesi Chen
https://doi.org/10.1002/anie.202500052, 2025
Published in: Angewandte Chemie International Edition
Tags: Cancer theranostics; CRISPR/Cas; gene carrier; gene editing; nucleic acid detection
Integrated spatial morpho-transcriptomics predicts functional traits in pancreatic cancer
Authors: Dennis Gong, Rachel Liu, Yi Cui, Michael Rhodes, Jung Woo Bae, Joseph M. Beechem, William L. Hwang
https://www.science.org/doi/pdf/10.1126/sciadv.adx0632
Published in: Science Advances (2025)
Tags: Cell painting, Phenotypic screening,