Scientific Publications

Peer-reviewed research using Nanolive imaging

Discover a list of peer-reviewed scientific publications using Nanolive imaging in the fields of drug discovery, cell metabolism, etc.

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  • Low biological fluctuation of mitochondrial CpG and non‑CpG methylation at the single‑molecule level

    Authors: Chloe Goldsmith, Jesús Rafael Rodríguez-Aguilera, Ines El-Rifai, Adrien Jarretier, Valérie Hervieu, Victoria Chagoya de Sánchez, Robert Dante, Gabriel Ichim, Hector Hernandez-Vargas

    https://doi.org/10.1038/s41598-021-87457-8, 2021

    Published in: Scientific Reports

    Tags: Nanopore sequencing; DNA methylation; mtDNA; metabolism; hepatocytes; differentiation; oxidative stress; 5mC; long-read sequencing

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  • NOX4 promotes ferroptosis of astrocytes by oxidative stress-induced lipid peroxidation via the impairment of mitochondrial metabolism in Alzheimer’s diseases

    Authors: M.W. Park, H.W. Cha, J. Kim, J.H. Kim, H. Yang, S. Yoon, N. Boonpraman, S.S. Yi, I.D. Yoo, J.-S. Moon

    https://doi.org/10.1016/j.redox.2021.101947, 2021

    Published in: Redox Biology

    Tags: NOX4, Ferroptosis, Mitochondrial metabolism, Oxidative stress, Alzheimer’s disease

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  • Biological autoluminescence as a noninvasive monitoring tool for chemical and physical modulation of oxidation in yeast cell culture

    Authors: Martin Bereta, Michal Teplan, Djamel Eddine Chafai, Roman Radil, Michal Cifra

    https://doi.org/10.1038/s41598-020-79668-2, 2021

    Published in: Scientific Reports

    Tags: biological autoluminescence (BAL); Saccharomyces cerevisiae; Fenton reagents; cell metabolism

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  • Variations of intracellular density during the cell cycle arise from tip-growth regulation in fission yeast

    Authors: Pascal D OdermattTeemu P Miettinen Joël Lemière Joon Ho Kang Emrah Bostan Scott R Manalis Kerwyn Casey Huang Fred Chang

    https://doi.org/10.7554/eLife.64901, 2021

    Published in: eLife

    Tags: cell cycle; dry-mass; cell cycle arrest; osmosis

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  • Spatiotemporal changes in mechanical matrisome components of the human ovary from prepuberty to menopause

    Authors: E. Ouni, C. Bouzin, M.M. Dolmans, E. Marbaix, S. Pyr dit Ruys, D. Vertommen, C.A. Amorim

    DOI: https://doi:10.1093/humrep/deaa100, 2020

    Published in: Human Reproduction

    Tags: Ovary, extracellular matrix, hormone replacement therapy, CX, aging, fertility preservation, mechanobiology, elastic matrisome, matrisome, collagen, elastin, EMILIN-1, fiblilin-1, glycosaminoglycan, GAGs, folicle, ECM

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  • Bicalutamide Elicits Renal Damage by Causing Mitochondrial Dysfunction via ROS Damage and Upregulation of HIF-1

    Authors: Kuan-Chou Chen, Chang-Rong Chen, Chang-Yu Chen, Kai-Yi Tzou, Chiung-Chi Peng, Robert Y. Peng

    DOI: https://doi.org/10.21873/anticanres.14232, 2020

    Published in: Anticancer Research

    Tags: Oncology and immunooncology, cell metabolism, CX, PC-3 Pca, bicalutamide, Bic, rat mesangial cell, RMC line, mitochondrial dysfunction, HIF-1, oxygen consumption rate, OCR, mitochondria, pgrostate cancer, Pca, cardiovascular damage, renal damage, lactate cehydrogenase, ROS, lysosome, BCL2, caspase-3

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  • The antimicrobial peptide tilapia piscidin 3 induces mitochondria-modulated intrinsic apoptosis of osteosarcoma cells

    Authors: Chien-HanYuan, Yi-LingMa, Po-ChangShih, Chao-TingChen, Shu-YuCheng, Chieh-YuPan, Yen-HsuanJean, Yih-MinChu, Sung-ChunLin, Yu-ChengLai, Hsiao-MeiKuo

    DOI: https://doi.org/10.21873/anticanres.14232, 2020

    Published in: Biochemical Pharmacology

    Tags: Immunooncology, oncology, cell metabolism, OS MG63, osteosarcoma, intrinsic apoptosis, TP3, antimicrobial peptide, mitochondria, caspase, blebbing, shrinkage, nuclear fragmentation, chromatin condensation, apoptopodia, ROS, acidification, fission, fusion

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  • Feature Application: Characterizing cell metabolism

    This Feature Application highlights the huge potential of Nanolive cell imaging for metabolic studies. We begin by proving that mitochondria and LDs have specific RI signals that allow them to be identified and mapped, in 3D (case study 1). We show that it is possible to image fission-fusion dynamics in mitochondria (case study 2), induce and detect mitochondrial dysfunction (case study 3) and then restore mitochondrial function by the addition of a specific drug (case study 4). Finally, we show that it is possible to quantify LD dynamics in unperturbed (case study 5) and drug-perturbed conditions (case study 6).

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  • Bioenergetics Consequences of Mitochondrial Transplantation in Cardiomyocytes

    Authors: Paria Ali Pour, M. Cristina Kenney and Arash Kheradvar

    DOI: https://doi.org/10.1161/JAHA.119.014501, 2020

    Published in: Journal of the American Heart Association

    Tags: Mitochondria and cell metabolism, mitochondrial transplantation, cardiac patients, cardiology, ATP, non-autologous, acute stress

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  • Advancing methods for the analysis of glioblastoma cell motion using quantitative time lapse holographic imaging and cellular tomography

    Authors: Ed Luther, Livia Mendes, Nina Filiczak, Aditi Jhaveri, Lara Milane, Vladimir Torchilin

    DOI: https://doi.org/10.1117/12.2510236, 2019

    Published in: Society of Photo-Optical Instrumentation Engineers

    Tags: Neuroscience, Immunooncology & Oncology, mitochondria and cell metabolism, glioblastoma, motility, mitochondria, fission, fusion, nanotubes, spheroids

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