CD47 is a potent Don’t eat me signal that enables cancer cells to evade immune surveillance and killing by innate immune cells, such as macrophages. By using bispecific antibodies with a high affinity targeting arm (against a tumor-associated antigen, or TAA) and an...
We are happy to feature a new publication from users of Nanolive’s 3D Cell Explorer, located at the AGH University of Science and Technology (Kraków, Poland) and The University of Sydney (Australia). The effect of saturated fatty acids (FAs) on malignant and...
Ferroptosis is a new type of regulated cell death that was formally identified in 2012 [1]. It is an iron-dependent, non-apoptotic mode of cell death that is strongly linked to lipid metabolism. Since its discovery, Ferroptosis has been identified as a key regulator...
Cell-cell interactions between embryonic stem cells (ESCs) and trophoblast stem cells (TSCs) play a vital role in tissue formation in developing embryos [1]. The two cell types are known to communicate through the wnt/β-catenin signaling pathway [2], but identifying...
Could Mitochondrial transplantation into Cardiomyocytes be an effective treatment for cardiac disease? This paper shows the first test of transplanting non-autologous mitochondria from healthy skeletal muscle cells into normal cardiomyocytes. This transplant led to...
