Table of content Valproic acid (VPA): anticonvulsant, epigenetic modulator, potential cancer treatment? VPA interferes with metabolite usage often leading to steatosis Investigating changes in cell metabolism using Nanolive label-free, live cell imaging Nanolive...
What is Cdk2 and why is it an attractive anti-cancer target? Cyclin-dependent kinase 2 (Cdk2) plays an important role in the cell cycle, regulating the transition from the G1 phase where the cell grows and certain intracellular components (such as the centrosomes)...
In this footage, obtained using Nanolive’s 3D Cell Explorer-fluo we observe the progression of GFP-labelled adenovirus in human bone osteosarcoma epithelial (U2OS) cells. Adenovirus is known to migrate to the nucleus of its host cell where it forms structures known as...
Background In this case study, we expose cells to inhibitors or modulators of kinase activity and observe how the cells respond. Hyperactivity, malfunction or overexpression of kinases is the root cause of many human cancers, and so the development of kinase...
We are delighted to announce SIX exciting new articles featuring Nanolive’s 3D Cell Explorer. The articles come from users based in Taiwan, Poland, Spain, and Belgium, respectively. TP3, an antimicrobial peptide, inhibits infiltration and motility of glioblastoma...
