Background Chondrogenic differentiation describes how cartilage is formed from mesenchymal stem cells (MSCs). Cells pass two morphological stages; first they differentiate into chondroblasts, which then mature into chondrocytes. Chondroblasts are responsible for the...
Chondrogenic differentiation: from stem cell to cartilage Mesenchymal stem cells (MSCs) are multipotent stromal cells that can differentiate into a variety of cell types including osteoblasts (bone cells), neurones (nerve cells), chondrocytes (cartilage cells),...
Keratinocytes and Epidermis The outer layer of the skin, the epidermis, is composed mainly by keratinocytes, which represent around 90% of the cells in that layer[1], [2]. They play a role in immune responses, by acting as barrier and preventing the entrance of...
Cytokinesis, as we briefly introduced in our mitosis in Mesenchymal Stem Cells post, refers to the obtention of two separated daughter cells after mitosis[1]. The process of separation can coincide in time with anaphase and/or telophase, the two final steps in...
Since their description in the 1970s1, mesenchymal stem cells (MSC) have been at the center of very active research with the challenge of using them as therapy in organ and tissue repair. For that purpose, it has been essential to develop culture protocols that would...
